Brisbane superstar Lachie Neale will not feature again before the finals after suffering a quad injury.
But the Lions are confident co-captain Neale will be on target to return for the first week of the finals.
The dual Brownlow medallist was experiencing soreness following Brisbane’s 27-point win over Collingwood before scans revealed a tear in his quad.
Neale will miss Saturday’s clash against 10th-placed Sydney at the Gabba and matches against top-eight sides Fremantle (Optus) and Hawthorn (Gabba).
Brisbane have also lost defender Ryan Lester (concussion), with Tom Doedee shaping as a potential choice to replace the veteran.
Arriving from Adelaide in 2023, Doedee has not made his debut for the Lions after suffering setbacks while rehabilitating from a knee reconstruction.

Lachie Neale. (Photo by Quinn Rooney/Getty Images)
Elsewhere, Nick Larkey is in doubt for North Melbourne’s away clash against GWS after re-injuring his right knee.
On return from a PCL injury, the star forward aggravated his knee after landing heavily from an aerial contest in North’s nine-point defeat to St Kilda.
North captain Jy Simpkin is also experiencing inflammation of a tendon behind a knee but is listed as a test alongside first-year player Zac Banch (rib).
GWS have lost youngster Toby McMullin to a season-ending ankle injury, while lethal goalkicker Jesse Hogan continues to manage foot soreness.
Midfielder McMullin has undergone surgery for a syndesmosis injury he suffered in the Giants’ horror defeat to the Western Bulldogs.
© AAP